Two years after the dramatic conclusion of Final Fantasy VII, the ruins of Midgar stand as a testament to the sacrifices that helped bring peace. However, the world will soon face a new menace. A mysterious illness known as Geostigma is spreading fast. Old enemies are astir, aswell as new one's.

And Cloud, weighed down by memories of loved ones he has lost and his physical condition, now comes across as devoid of hope. He walked away from the life of a hero to live in solitude as a transporter for the Strife Delivery Service, which is located in 7th Heaven, and also functions as an orphanage for children stricken with the Geostigma illness. He must once again step forward...